Dr Phoebe McCrorie
Current positions
Post-Doctoral Research Fellow
Children’s Brain Tumour Research Centre, University of Nottingham
https://www.cbtrc.org/home.aspx
Qualifications
BSc (Hons) Biochemistry and Forensic Science, Keele University 2015
PhD, brain tumour drug delivery, University of Nottingham 2020
Short biography
Phoebe graduated from Keele University in 2015 with a first-class honours (BSc) in Biochemistry and Forensic Science, followed by graduating from the School of Pharmacy, University of Nottingham in 2020 with a PhD in the development of a local drug delivery system for glioblastoma.
Phoebe is currently a post-doctoral research fellow within the Children’s Brain Tumour Research Centre, University of Nottingham. She currently works on developing a 3D in vitro model for paediatric cerebellar brain tumours which closely recapitulates the in vivo tumour environment, with the goal of finding new drug targets based on RNA sequencing data.
Phoebe’s research interests lie within finding and delivering new and repurposed drugs for local drug delivery in both adult and paediatric brain tumours whereby there is a surgical resection. She supervises PhD and Masters students regularly and runs a monthly departmental seminar series within the Children’s Brain Tumour Research Centre.
Selected publications
McCrorie P, et al. Development of nanoparticle loaded microneedles for drug delivery to a brain tumour resection site. European Journal of Pharmaceutics and Biopharmaceutics. Volume 182, p. 53-61. 2023.
McCrorie P, et al. Detection of Label-Free Drugs within Brain Tissue Using Orbitrap Secondary Ion Mass Spectrometry as a Complement to Neuro-Oncological Drug Delivery. Pharmaceutics. Volume 14. P. 571. 2022.
McCrorie P, et al. Etoposide and olaparib polymer-coated nanoparticles within a bioadhesive sprayable hydrogel for post-surgical localised delivery to brain tumours. European Journal of Pharmaceutics and Biopharmaceutics. Volume 157. P. 108-120. 2020.