Professor Susan Short
Current Positions
Professor of Clinical Oncology and Neuro Oncology, University of Leeds and Leeds Teaching Hospitals Trust
Qualifications
MBBS BSc MRCP FRCR PhD
Short biography
Susan Short is an academic oncologist with a research interest in the treatment of adult brain tumours. This includes clinical research in technical radiotherapy developments as well as drug-radiotherapy combinations in early phase clinical studies. She is PI for a portfolio of local and national clinical studies. Her recent laboratory work has included investigation of oncolytic viruses as immune stimulants and adjuvants in gliomas, targeting micro-RNA biology in gliomas and identifying novel approaches to preventing DNA repair following cytotoxic treatments.
She has many years of experience in developing and leading major national clinical research groups including chairing the NCRI Brain Tumour Clinical Study Group, the NCRI CTRad pre-clinical workstream and the Clinical Committee of BNOS. She has been involved in collaborative network activity in EU FP7 (INSERT) as well as national radiotherapy research (ART-NET and RAD-NET) and national glioma consortia (BRAIN-MATRIX). She currently leads an international consortium addressing liquid biomarkers in glioma (BRAIN-LBC).
Selected publications
Twelves C, Sabel M, Checketts D, Miller S, Tayo B, Jove M, Brazil L, Short SC, GWCA1208 study group. 2021. A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma. British Journal of Cancer. 124(1), pp. 1379-1387
Weller M, van den Bent M, Preusser M, Le Rhun E, Tonn JC, Minniti G, Bendszus M, Balana C, Chinot O, Dirven L, French P, Hegi ME, Jakola AS, Platten M, Roth P, Rudà R, Short S, Smits M, Taphoorn MJB, von Deimling A, Westphal M, Soffietti R, Reifenberger G, Wick W. 2021. EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood. Nature Reviews Clinical Oncology. 18(3), pp. 170-186
Boissinot M, King H, Adams M, Higgins J, Shaw G, Ward TA, Steele LP, Tams D, Morton R, Polson E, da Silva B, Droop A, Hayes JL, Martin H, Laslo P, Morrison E, Tomlinson DC, Wurdak H, Bond J, Lawler SE, Short SC. 2020. Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300. Oncogene.
Wen PY, Weller M, Lee EQ, Alexander BA, Barnholtz-Sloan JS, Barthel FP, Batchelor TT, Bindra RS, Chang SM, Chiocca EA, Cloughesy TF, DeGroot JF, Galanis E, Gilbert MR, Hegi ME, Horbinski C, Huang RY, Lassman AB, Le Rhun E, Lim M, Mehta MP, Mellinghoff IK, Minniti G, Nathanson D, Platten M, Preusser M, Roth P, Sanson M, Schiff D, Short SC, Taphoorn MJB, Tonn J-C, Tsang J, Verhaak RGW, von Deimling A, Wick W, Zadeh G, Reardon DA, Aldape KD, van den Bent MJ. 2020. Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions. Neuro-Oncology.
Brazil L, Swampillai AL, Mak KM, Edwards D, Mesiri P, Clifton-Hadley L, Shaffer R, Lewis J, Watts C, Jeffries S, Gkogkou P, Chalmers AJ, Fersht NL, Hackshaw A, Short SC. 2020. Hydroxychloroquine and short-course radiotherapy in elderly patients with newly diagnosed high-grade glioma: a randomized phase II trial. Neuro-Oncology Advances. 2(1)
‘For more information …’ https://medicinehealth.leeds.ac.uk/medicine/staff/762/professor-susan-short