Treatment Pathways and Guidance

BNOS is keen to assist its members in highlighting for them current guidelines for management of CNS neoplastic disease. We have ranked these guidelines into three levels:

  1. UK ‘must be complied with’ guidelines,
  2. Recommended best UK practice guidelines
  3. International recommended best practice guidelines.

The following clinical links might be helpful to members.


1. UK essential standards for clinical practice

Adult suspected brain tumours: The 2006 NICE IOG: “Improving Outcomes for People with Brain and other CNS Tumours” (June 2006) – pdf download


2. UK recommendations for clinical practice

For children

Royal College of Paediatrics and Child Health Pathways to Diagnosis: The Diagnosis of Brain Tumours 2008

This document is supplemented by the more recent ‘Head Smart’ campaign: “Head smart be brain tumour aware”.


Royal College of Pathologists: Standards and datasets for reporting cancers

Dataset for tumours of the central nervous system, including the pituitary gland (4th Edition) January 2016


3. International best practice guidelines




European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma (The Lancet Oncology, June 2017)

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas (The Lancet Oncology, June 2017)

Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO) (SNO Neuro-oncology February 2017)

EANO guidelines for the diagnosis and treatment of meningiomas (published in Lancet Oncology September 2016)

Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas (first published April 2016)

EANO has published two sets of guidelines for management of glioma:

For high grade glioma –

EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma” 2014

For low grade glioma –

Guidelines on management of low-grade gliomas: report of an EFNS–EANO Task Force” 2010





The Neurologic Assessment in Neuro-Oncology (NANO) scale: a tool to assess neurologic function for integration into the Response Assessment in Neuro-Oncology (RANO) criteria (SNO Neuro-oncology April 2017)

Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors” Report of the Quality Standards Subcommittee of the American Academy of Neurology.

Radiation Therapy for Glioblastoma: Executive Summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline