Dr Samantha Mills

Current Positions

Consultant Neuroradiologist, The Walton Centre NHS Foundation Trust

Qualifications

BSc Hons Neuroscience, University of Manchester, 1995
MBChB, University of Manchester, 1998
MRCP, Royal College of Physicians (London), 2002
FRCR, Royal College of Radiologists, 2005
PhD, University of Manchester, 2010

Introduction

Dr Mills became a Consultant Neuroradiologist in January 2011 after completing her clinical training in Neuroradiology (Manchester Radiology Training Scheme). Prior to this she held a joint RCR/CRUK Clinical Research Fellowship, undertaking a PhD in advanced magnetic resonance imaging of adult brain tumours using novel MR techniques, including dynamic contrast enhanced MRI, diffusion imaging and oxygen enhanced MRI at the University of Manchester. Her academic interests include neuro-oncology, imaging biomarkers and translational research. In October 2014, she moved to the Walton Centre NHS Foundation Trust, Liverpool.

Committees

NCRI (National Cancer Research Institute) Brain Tumour Clinical Studies Group and Imaging and Technology subgroup

RCR (Royal College of Radiologists) Standardised Oncology Reporting Group, Brain representative

Selected Publications

Gallagher MJ, Jenkinson MD, Brodbelt AR, Mills SJ, Chavredakis E. WHO grade 1 meningioma recurrence: Are location and Simpson grade still relevant? Clin Neurol Neurosurg. 2016 Feb;141:117-21

Mills SJ, du Plessis D, Pal P, Thompson G, Buonacorrsi G, Soh C, Parker GJ, Jackson A. Mitotic Activity in Glioblastoma Correlates with Estimated Extravascular Extracellular Space Derived from Dynamic Contrast-Enhanced MR Imaging. AJNR Am J Neuroradiol. 2015 Dec 24. [Epub ahead of print]

Stivaros SM, Stemmer-Rachamimov AO, Alston R, Plotkin SR, Nadol JB, Quesnel A, O’Malley J, Whitfield GA, McCabe MG, Freeman SR, Lloyd SK, Wright NB, Kilday JP, Kamaly-Asl ID, Mills SJ, Rutherford SA, King AT, Evans DG. Multiple synchronous sites of origin of vestibular schwannomas in neurofibromatosis Type 2. J Med Genet. 2015 Aug;52(8):557-62.

Smith MJ, Isidor B, Beetz C, Williams SG, Bhaskar SS, Richer W, O’Sullivan J, Anderson B, Daly SB, Urquhart JE, Fryer A, Rustad CF, Mills SJ, Samii A, du Plessis D, Halliday D, Barbarot S, Bourdeaut F, Newman WG, Evans DG. Mutations in LZTR1 add to the complex heterogeneity of schwannomatosis Neurology. 2015 Jan 13;84(2):141-7

Linnik IV, Scott ML, Holliday KF, Woodhouse N, Waterton JC, O’Connor JP, Barjat H, Liess C, Ulloa J, Young H, Dive C, Hodgkinson CL, Ward T, Roberts D, Mills SJ, Thompson G, Buonaccorsi GA, Cheung S, Jackson A, Naish JH, Parker GJ. Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma. Magn Reson Med. 2014 May;71(5):1854-62.

Mills SJ, Thompson G, Jackson A. Imaging biomarkers of cerebral metastases. Cancer Imaging. 2012 Aug 10;12:245-52.

Thompson G, Mills SJ, Coope DJ, O’Connor JP, Jackson A. Imaging biomarkers of angiogenesis and the microvascular environment in cerebral tumours. Br J Radiol. 2011 Dec;84 Spec No 2:S127-44.

Thompson G, Mills SJ, Stivaros SM, Jackson A. Imaging of Brain Tumors: Perfusion/Permeability. Neuroimaging Clinics of North America 2010 Aug;20(3):337-53.

Mills SJ, Soh C, O’Connor JP, Rose CJ, Buonaccorsi GA, Cheung S, Zhao S, Parker GJM, Jackson A. Enhancing Fraction in Glioma and its relationship to the tumoural vascular microenvironment: A Dynamic Contrast Enhanced Magnetic Resonance Imaging Study. AJNR Am J Neuroradiol 2010: Apr;31(4):726-31.

Mills SJ, Soh C, Rose CJ, Cheung S, Zhao S, Parker GJ, Jackson A. Candidate Biomarkers of Extravascular Extracellular Space: A Direct Comparison of Apparent Diffusion Coefficient and Dynamic Contrast-Enhanced MR Imaging-Derived Measurement of the Volume of the Extravascular Extracellular Space in Glioblastoma Multiforme. AJNR Am J Neuroradiol 2010 Mar;31(3):549-53

Mills SJ, Soh C, O’Connor JP, Rose CJ, Buonaccorsi GA, Cheung S, Zhao S, Parker GJ, Jackson A. Tumour enhancing fraction (EnF) in glioma: relationship to tumour grade. Eur Radiol. 2009 Jun;19(6):1489-98.

Jackson A, O’Connor J, Thompson G, Mills S. Magnetic resonance perfusion imaging in neuro-oncology. Cancer Imaging. 2008 Oct 13;8:186-99.

Mills SJ, Patankar TA, Haroon HA, Balériaux D, Swindell R, Jackson A. Do cerebral blood volume and contrast transfer coefficient predict prognosis in human glioma? AJNR 2006 Apr;27(4):853-8.

Patankar TF, Haroon HA, Mills SJ, Balériaux D, Buckley DL, Parker GJ, Jackson A. Is volume transfer coefficient (K(trans)) related to histologic grade in human gliomas? AJNR 2005 Nov-Dec;26(10):2455-65.