Working together to beat
Nervous system tumours

Quality neuro-oncology education

Major UK based neuro-oncology
annual meetings

To promote high-quality neuro-oncology research, education and multi-disciplinary patient centred care

Understanding brain tumours to ensure the very best care is provided to all patients.

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Research News

Tiny packages may pack powerful treatment for brain tumours

| Scientific/Research | No Comments

23 May 2016 Glioblastoma multiforme is a devastating disease with no curative options due to several challenges. The brain tumour has a significant overall mortality, in part due to its…

Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers

| Scientific/Research | No Comments

23 May 2016 Glioblastoma multiforme is a devastating disease with no curative options due to the difficulty in achieving sufficient quantities of effective chemotherapies into the tumor past the blood–brain…

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma

| Scientific/Research | No Comments

23 May 2016 Genomic mapping has driven the classification of glioblastoma into distinct molecular subclasses, but mechanisms that regulate tumor subclass phenotypes are only now emerging. In this issue of…

Gene therapy against brain cancer

| Scientific/Research | No Comments

23 May 2016 Antonello Mallamaci and his group at SISSA have just published highly promising results on the application of gene therapy against glioblastomas, a family of brain tumours among…

Clinical Practice

Final results of the second prospective AIEOP protocol for pediatric intracranial ependymoma

| Clinical | No Comments

23 May 2016 This prospective study stratified patients by surgical resection (complete = NED vs incomplete = ED) and centrally reviewed histology (World Health Organization [WHO] grade II vs III)….

The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review

| Clinical | No Comments

23 May 2016 5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North America. A systematic review was conducted to assess the…

Reporting of patient-reported health-related quality of life in adults with diffuse low-grade glioma: a systematic review

| Clinical | No Comments

23 May 2016 Patient-reported health-related quality of life (HRQoL) analysis can provide important information for managing the balance between treatment benefits and treatment-related adverse effects on quality of life (QoL)….

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

| Clinical | No Comments

23 May 2016 The 2016 World Health Organization Classification of Tumors of the Central Nervous System is both a conceptual and practical advance over its 2007 predecessor. For the first…